We create fit-for-purpose prosthesis control solutions. Acquiring a new skill, for example, learning to use chopsticks, requires accurate motor commands to be sent from the brain to the hand, and reliable sensory feedback from the hand to the brain. Over time and with training, the brain learns to handle this two-way communication flexibly and efficiently. Inspired by this sensorimotor interplay, our research is guided by a conviction that progress in prosthetic limb control is best achieved through a strong synergy of motor learning and sensory feedback.We, therefore, study the interaction of neural and behavioural processes that control the hand movements to ultimately innovate digitally-enabled prosthetic control solutions that users would find fit for purpose. Specifically, we are developinga data-driven care model that enhances the experience of receiving a prosthesis.novel methods and technologies enable the utilisation of the flexibility of the brain in learning new skills for closed-loop prosthesis control;efficient artificial intelligence algorithms for processing of multi-modal data collected with hybrid sensors;effective systems and stimulation paradigms to restore sensory feedback in prosthetic control;Current researchMachine Learning for Prosthetic Hand ControlWe have worked on several classes of upper limb prosthetics controllers to design most intuitive control interfaces. Moreover, we have developed new ways of combining multi-modal bio-signals to improve intuitive control of prosthetics.The main focus has been to improve the control of prosthetics by the use of machine learning methods.AT-Myo: Arm translation in electromyography (submitted) 2024. PDFTemporal convolutional networks for myoelectric control (submitted) 2024. PDFPlug-and-play myoelectric control via a self-calibrating random forest common model (submitted) 2024. PDFPosture-invariant myoelectric control with self-calibrating random forests Front Neurorobotics 18:1462023, 2024 PDFDigital sensing systems for electromyography IEEE Trans Neural Sys Rehab Eng 32:2826-2834, 2024. PDFExplainable AI-powered graph neural networks for HD EMG-based gesture intention recognition IEEE Trans Cons Elec 70(1):4499-4506, 2024 PDFOne-shot random forest model calibration for hand gesture decoding J Neural Eng 21(1):016006, 2024. PDFExplainable and robust deep forests for EMG-force modeling IEEE J Biomed Health Informatics 27(6):2841-2852, 2023. PDFRecalibration of myoelectric control with active learning Front Neurorob 16, 277, 2022. PDFDiscrete action control for prosthetic digits IEEE Trans Neural Sys Rehab Eng, 30:610-620, 2022. PDFMulti-grip classification-based prosthesis control with two EMG-IMU sensors, IEEE Trans Neural Sys Rehab Eng, 28(2):508-518, 2020. PDFImproved prosthetic hand control with concurrent use of myoelectric and inertial measurements, J NeuroEng Rehab, 14:71, 2017. PDFHuman Learning for Prosthetic Hand ControlWhen controlling a prosthesis, the patterns of neural and/or muscular activity can differ from those used to control the biological limbs. We explore the extent to which this activity can deviate from natural patterns employed in controlling the movement of the biological arm and hand. We will therefore examine whether prosthesis users can learn to synthesise new functional maps between muscles and prosthetic digits; for instance, in the case of a partial hand amputation, whether users can grasp an object by contracting a small group of muscles that do not naturally control the grasp.We have named this approach Abstract Decoding. In this definition, the user learns to generate functional muscle activity patterns. This notion is completely in contrast to the pattern recognition or regression approaches in which the prosthesis learns to identify movement intent(s) by decoding the EMG patterns without considering the users’ learning capability.DistaNet: Grasp-specific distance biofeedback promotes the retention of myoelectric skills J Neural Eng 21(3):036037, 2024 PDFReducing motor variability enhances myoelectric control robustness across limb positions IEEE Trans Neural Sys Rehab Eng, 32:23-32, 2024 PDFDelaying feedback during pre-device training facilitates the retention of novel myoelectric skills, J Neural Eng 20(3):036008, 2023 PDFLearning, generalisation, scalability of abstract myoelectric control, IEEE Trans Neural Sys Rehab Eng, 28(7):1539-1547, 2020 PDFMyoelectric control with abstract decoders, J Neural Eng, 15(5):056003, 2018 PDFArtificial proprioceptive feedback for myoelectric control, IEEE Trans Neural Sys Rehab Eng, 23(3):498-507, 2014 PDFAbstract and proportional myoelectric control for multi-fingered hand prostheses, Ann Biomed Eng, 41(12):2687-2698, 2013 PDFFlexible cortical control of task-specific muscle synergies, J Neurosci, 32(36):12349-12360, 2012 PDFProsthetic Control Beyond LaboratoryIn current clinical practice, a prosthesis is fitted in the clinic. Once the user is home, the clinician “cannot” tell if the prosthesis is used or how well it is functioning. Statistics show that up to 44% of the users abandon their prosthesis [Salminger et al. Disability & Rehab, 2020].We aim to co-create the world’s first Internet-enabled prosthetic hand; connecting the user and the clinic seamlessly. Secure data flow and artificial intelligence (AI) sit at the heart of this bidirectional communication link. The opposite figure illustrates our vision. Internet of Things for beyond-the-laboratory prosthetics research, Phil. Trans. R. Soc. A.38020210005, 2022 PDFArduino-based myoelectric control: Towards longitudinal study of prosthesis use, Sensors 21(3):763, 2021 PDF Research FundingSelected ProjectsBionics+: User-Centred Design and Usability of Bionic DevicesEPSRC (2021-2025)A smart electrode housing to improve the control of upper limb myoelectric prosthesesNIHR (2021-2024)Sensorimotor learning for control of prosthetic limbsEPSRC (2018-2024)FacilitiesLabortoray EquipmentsElectrophysiologyBlackrock MicrosystemsNeuroport (FDA)CerebusCereStimUtah Array Pneumatic InserterA-M SystemsDifferential AC Amplifier (Model 1700)Isolated Pulse Stimulator (Model 2100)DelsysTrigno Avanti Mobile (CE)DigitimerD360 Amplifier (CE)DS7A stimulators (CE, FDA)Prosthetic HandsCOVVI ltdNEXUS (CE)ÖssurRoboLimb (CE)OtherTurntableCrayfish 60CybergloveCyberglove IISetups for Outcome MeasurementSHAPBox and Blocks This article was published on 2024-10-15